Management of cutaneous metastases using electrochemotherapy

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Management of cutaneous metastases using electrochemotherapy

BACKGROUND Cutaneous metastases may cause considerable discomfort as a consequence of ulceration, oozing, bleeding and pain. Electrochemotherapy has proven to be highly effective in the treatment of cutaneous metastases. Electrochemotherapy utilises pulses of electricity to increase the permeability of the cell membrane and thereby augment the effect of chemotherapy. For the drug bleomycin, the...

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electrochemotherapy for treatment of cutaneous breast cancer metastases: a review

background: electrochemotherapy is a relatively new technique in the treatment of skin metastases that are not amenable to conventional therapy. its use in breast cancer is now established in many european centers. methods: published literature of electrochemotherapy in terms of its scientific basis, current clinical practice of breast cancer treatment providers, as well as the future direction...

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Electrochemotherapy in Experimental Bone Metastases

INTRODUCTION: The skeleton is a common site of metastases for a number of different cancers. They include lung, breast, prostate, kidney, thyroid cancers and multiple myeloma. It has been reported that in 70% of patients with metastatic breast cancer, bone metastases will develop [1]. Cancer cells in bone disrupt normal bone remodelling, resulting in the case of breast tumour cells in osteolyti...

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Intraoperative electrochemotherapy of colorectal liver metastases.

BACKGROUND AND OBJECTIVES Electrochemotherapy is effective in treatment of various cutaneous tumors and could be translated into treatment of deep-seated tumors. With this aim a prospective pilot study was conducted to evaluate feasibility, safety, and efficacy of intraoperative electrochemotherapy in the treatment of colorectal liver metastases. METHODS Electrochemotherapy with bleomycin was...

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Effective treatment of multiple unresectable skin melanoma metastases by electrochemotherapy.

Multiple unresectable melanoma skin metastases pose a treatment problem, especially in centers where isolated limb perfusion is not available. We report the case of a 59-year-old woman who developed multiple small unresectable cutaneous melanoma metastases on the thigh after her lower limb was amputated. Electrochemotherapy with bleomycin resulted in good local control of the disease, with a co...

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ژورنال

عنوان ژورنال: Acta Oncologica

سال: 2011

ISSN: 0284-186X,1651-226X

DOI: 10.3109/0284186x.2011.573626